Thanks for the response it is appreciated . I have had mo reactions to Casodex. Issue is the Oncologist I started with in Richmond only prescribed 30 days of Casodex and midway start a 6 month injection of Lupron. I was moved to Tappahannock to shorten my drive for treatment. The new Oncologist wants me on both Xtandia and Lupron. Will see how the old bod tolerates the meds. I plan to ho bavk to the Y for more weight bearing exercises. Since other half has dementia most of my time is taking care of her. Thanks again for responding. Will let you know how things turnout. By the way used to ride a Honda until it was stolen.