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PMR - How will I know I am in remission?
Polymyalgia Rheumatica (PMR) | Last Active: May 12, 2023 | Replies (43)Comment receiving replies
IL-6 regulation is an interesting topic. I take a biologic called Actemra which is an IL-6 receptor antagonist to control my symptoms of PMR along with other autoimmune problems. I was able to taper off prednisone after taking it for 13 years of PMR. Now I want to wean myself off Actemra even though I haven't had any side effects. I have tried stopping Actemra but my symptoms return.
Replies to "IL-6 regulation is an interesting topic. I take a biologic called Actemra which is an IL-6..."
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Actemra is a IL6 receptor antagonist so is not illeminating the source of the IL6 but rather interfering with your reaction to it. I am in the process of reading vollumn II of the LDN research book and it indecates that biologics may effect the immune system adversly. In a sense, you need to normalize your system before getting off of Actemra. Low Dose Naltrexone really helps with that. Also, the MSM (which doesn't require a script and is Genrally Regarded As Safe) actually lowers the output of IL6 (as does LDN, through its affect on the microglia). I would suggest you take MSM awhile before you try again and also read up on LDN and ask your rheumy for it if you think it is right for you. It is very safe, too.