Olease get a second opinion. It's very important. Also always advocate for him!!

Hi @deec2, welcome. I've moved your message about your husband's recent diagnosis of pancreatic cancer with liver metastatsis to this existing discussion:
- Just diagnosed pancreatic cancer stage 4 https://connect.mayoclinic.org/discussion/just-diagnosed-pancreatic-cancer-stage-4/

I did this so you can easily connect with other members like @nunz12 @dubbscopper @tpl @mayoconnectuser1 @huilim @helenar @lfitz @susanpmadigan @jessieleigh @mgilson and more who can share their experiences and journey with you and help to shine a light on what to expect.

You may also be interested in these related discussions:
- Radioembolization for pancreatic cancer metastasis to liver? https://connect.mayoclinic.org/discussion/radioembolization/
- Anyone on Gemcitabine with Abraxane? How long? Effective? https://connect.mayoclinic.org/discussion/gemcitabine-and-abraxane/

Dee, you can see, there are treatments options available. Where there are options, there is hope. Do you know what kind of chemotherapy he will be starting?

You may not want to hear this - I certainly didn't when my husband was diagnosed, but it is almost impossible to know what to expect. Patients responses and side effects are so varied and I haven't found any research to predict which path they will take. Some are almost debilitated by folfirinox and some are only fatigued with some neuropathy - same thing with gemcitabine/ abraxane. Some have an excellent response to one or the other or both and some do not. I have found nothing to predict who will react in which way.
While researching, I kept running across posts saying Don't Lose Hope! but my thoughts were always - It's stage 4 PC, there is almost no hope. Here we are 6 months later. My husband has responded very well to folfirinox and feels much better than he did before chemo. We have found a doctor willing to try innovative treatments (and who also isn't convinced the spots on the liver are mets) and I finally have some of that hope that I had initially lost. That is our 4th opinion.
I think the best advice I can give you is to do all the research that you can but keep in mind that PC's path is very unpredictable, don't lose hope as you read all those posts with unfavorable outcomes, get as many opinions as you can (not all doctors have the same knowledge), contact pancan.org and get genetic testing done, spend your time together doing the things you want.