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Anyone on Gemcitabine with Abraxane? How long? Effective?
Pancreatic Cancer | Last Active: 5 days ago | Replies (171)Comment receiving replies
I have a similar question. Previously fit and active 68 year old Spouse was told there was no effect from 5 months/10 infusions of Folfirinox before laparoscopic Whipple this November (several setbacks). Its pathology report showed 4/31 lymph nodes involved. Margins clear. Tumor 2.7 cm. Moderately differentiated. CA-19-9 levels went from 35 when diagnosed in April with adenocarcinoma, stayed at 80 for several months, but now has dropped to 10 while he is recovering from surgery. Told not to place too much stock in blood test. He is now walking a couple miles a day. Few digestive issues.He will resume with 6 months of Gemcitabine/Abraxane regime at end of month. Cancer type is not typical BRCA or RAS, but BRAF. Anyone with a similar history or comment on clinical targeted therapy, etc.?
Replies to "I have a similar question. Previously fit and active 68 year old Spouse was told there..."
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Hello, I have heard that there are targeted therapy clinical trials out there for a BRAF mutation, but am not 100% sure, as I am not a doctor. In other words, I've heard that it is considered "potentially actionable". A qualified pancreatic cancer specialist oncologist should be able to help you find clinical trials that would be potentially helpful. Please make sure you are seeing a top research pancreatic oncologist and a major cancer center such as Sloan Kettering, Johns Hopkins, MD Anderson, Cedars, or Mayo. If you are getting care at a non-cancer center hospital, they probably won't be able to help much with clinical trials. If the mutation is actionable, it may be a positive game changer for your spouse's medical care. You can also search for clinical trials on the clinical trial government homepage or call PANCAN for help. Please do not delay this search, as it could end up being very helpful. Please let me know if you have any questions.