I am sorry, But I never thought mNRA shots did change your DNA just all the gossip regarding them. I have had all that were available to me. I think they change dosage of chemo and Neulasta depending on blood work. What he told me was the reason I was given the dexamethasone is for nausea and since not having any, dropping the dosage may make bone pain less. Just something to try. And, he told me to add Benadryl at night may help with side effects. They give it to me with IV on chemo day. Never said to use before after. Will know more tomorrow. Was just called and simulation for radiation is now set for 12/27 at 10 am.