Treating the disease should also include treating the patient. I think this sometimes gets lost in the treatment of the disease. It has for me.

I've found the first 6 months on Lupron quite debilitating. Certainly I'm pleased to find testosterone at zero in three months and PSA cut in half, and PSA zeroing out after six months. So, Lupron treatment markers are promising. However, the weakness, loss of energy, muscle loss and weight gain have been dramatic, as are their impact on patient quality of life. I realize now no-one thought to mention any patient management or mitigation strategies for the effects of Lupron treatment. Actually, I don't recall having been shown any data justifying this treatment, although I'm sure some exists (I haven't done an internet search yet). I wonder what the facts are so I can balance the decision on this treatment.

I'm wavering on my next three month dose of Lupron (out of 18 months planned) and whether perhaps I should "detox" from this treatment. Any guidance on potential mitigation strategies? Pros and cons of ADT and length of time? The alternative is rolling the dice on dropping a treatment that is not curative, but clearly debilitative?