I have had one infusion of 400mg Reclast a long time ago, no more. I tolerated it ok. I continued then with Alendronate I do know most important is that it has to be infused slowly. I asked for that. I had no kidney problems. You have to have your Calcium and Parathyroid measured after, that changes temporarily. One infusion improved my values in my spine a lot, so that was really positive. I had not researched this drug prior to taking it, nor, as I said earlier, did I know, that from that time forward, no dentist would want to pull a tooth anymore in my mouth, even 9 years later. Because of the dental aspect alone I would not take it again. Later, I read patients who had many infusions are the ones who seem to have significant problems.

I just finished my 3rd or 4th one time a year infusion of Reclast. I have had no SE of any kind. HAD A DEXA-Scan few months ago most OP sites were slightly improved. But, my right hip got significantly worse. No known reason. Now, they want me to start Evenity. The possible SE scare me to death!!!