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Estradiol levels with AI

Breast Cancer | Last Active: Feb 27 5:02pm | Replies (35)

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@windyshores

Again, the study above says side effects were the same for all doses tested. Not sure how this relates to the other comment in the study about toxicity.

The insert that comes with Femara states that 20% of the dose reduced estradiol below detectable levels. My doc okayed every other day.

The question would seem to be, is estrogen suppression the only reason for side effects? If the study found similar side effects at all doses tested, it would seem so, but that is the question I wondered about.

I don't know if side effects would be better on a lower dose. I didn't have bad ones on the full dose so I stuck with it for 5 years.

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Replies to "Again, the study above says side effects were the same for all doses tested. Not sure..."

Wondering if possible reduction in side effects might be related to those we dont experience everyday such as bone loss or elevated cholesterol. Less med might be less problems for bones.

I am on Letrozole, it will be a year at the end of March. I have had my estradiol checked numerous times. My last one was 16 but has been as high as 33 and as low as .68. Who knows what it should be?