Thank you, Colleen. I was diagnosed with PN a couple years ago at Mayo Clinic and it has become more severe. I feel fortunate to only have to deal with it at night, when I have severe leg and foot cramps that continually interrupt my sleep. For the past week, I have been going to a chiropractor, who has completely eliminated the cramps with spinal adjustments, Tens treatments and the nightly application of a roll-on solution called Muscle Pain. It has done wonders for my sleep and attitude. I am a very active 115 lb. 77 year young female and am not ready to sit down. I know the condition will progressively get worse, but want to be prepared for what to do by reading this site to see what others are doing. Thank you for taking the time to help your community.