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Estradiol levels with AI

Breast Cancer | Last Active: Feb 27 5:02pm | Replies (35)

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@cashemire

So that means there is still some circulating Anastrozole until as long as 4 days after the med?
I am sure my surgeon/oncologist would not be happy with me, but I am just starting out with Arimidex and am taking the pill every other day (and even skipped more days this first week).
It seems logical that different doses would be necessary depending on things like body size, amt of circulating estradiol, etc, rather than one size fits all....
I wonder how one can get the very sensitive test of circulating estradiol done, as was apparently done in the study? Maybe I would have to get in to see an endocrinologist??
In another study, it was found that women trying to get pregnant did not have any more recurrences (compared to control group) when stopping adjuvant therapy for as long as 2 yrs, at least at the 3-year follow up period.
All of this is food for thought!

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Replies to "So that means there is still some circulating Anastrozole until as long as 4 days after..."

That’s an interesting finding about women trying to get pregnant!

I’m 99 and 98% estrogen positive ( two tumors) so I’m reliable about taking the meds. I did not need chemo and I declined radiation ( was questionable) so this is my one post surgical remedy so to speak. I’m grateful that I’m not having any observable side effects right now … just started month 8.