I did 5 years and felt safe on it. I did not have significant side effects. I found that walking, at first, hurt a bit but if I kept going for more than 20 minutes I felt great. My oncologist said she heard that from others.

I already had osteoporosis. On Femara, I was not medicated for bones (long story). There was a dip when I went on it, in bone density, that then levelled off (if not entirely since after menopause this happens).

Sometimes I think I felt better while on it and certainly felt safer so at first, when I went off, I actually missed it!

I react to fillers so I took brand name but toward the end of my 5 years I did find a generic I could take.

I am 8 years out and dealing with bones with Tymlos.

ps the Breast Cancer Index did not support me doing any extended hormonal treatment so I stopped at 5 years. I read that 7 is as good as 10, if it is useful to extend.