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Experience with Methotrexate?

Polymyalgia Rheumatica (PMR) | Last Active: Jan 31, 2023 | Replies (91)

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@marieirene

I’m now up to eight 2.5 methotrexate tabs once a week from six. My head is a bit off or dizzy with the increase. I’ll try one more time before I call rhumy. Very attentive & blood tests with scans often. Still at 13mg prednisone. Going to try 12 in a week to taper. Any suggestions?

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Replies to "I’m now up to eight 2.5 methotrexate tabs once a week from six. My head is..."

I had issues with lightheadedness while on methotrexate. Saw every specialist they could think of since that is not a side effect of the drug. All their tests were negative. We finally decided to discontinue the drug and I feel so much better. However, the methotrexate did get my inflammation markers to be normal for the first time in years. Getting labs next week and hoping my numbers are still down. Still on a low dose of prednisone, slowly tapering down.
Hope you get some answers and feel better.