Hello @rohitkachroo - Welcome to Mayo Clinic Connect. I hope someone on Connect can help you with your question. The Car T treatment I had was for large B cell lymphoma. I am not aware of Car T being used for solid tumors as that is my understanding of what you are asking, though treatments change continually.

I would suggest asking your heath care providers who should be able to provide some information and guidance to you.

Are you, or someone you know currently undergoing treatment?

@rohitkachroo, it sounds like you or your loved one has triple negative breast cancer that has now metastacized to the brain (BM) and developed leptomeningeal disease (LMD). @grandpabob is correct that the use of CAR-T is still in the research stage for solid tumors.

I found this article
– CAR-T Trial for Triple-Negative Breast Cancer Under Way https://www.cancertherapyadvisor.com/home/news/conference-coverage/san-antonio-breast-cancer-symposium-sabcs/sabcs-2018/car-t-trial-for-triple-negative-breast-cancer-under-way/

Trials for CAR-T for TNBC are in early phases (phase 1) as yet.

Here is a recent article about promising research at Mayo Clinic for TNBC:
– Mayo researchers identify potential new treatment for subset of women with triple-negative breast cancer https://newsnetwork.mayoclinic.org/discussion/mayo-researchers-identify-potential-new-treatment-for-subset-of-women-with-triple-negative-breast-cancer/

You can find more clinical trials being conducted currently at Mayo Clinic for triple negative breast cancer here: https://www.mayo.edu/research/clinical-trials/search-results?keyword=triple%20negative%20breast%20cancer