Brunner's gland hyperplasia

Hi @lakelady55 and welcome to Mayo Clinic Connect. I see that you are looking for Brunner's symptoms and treatment.
Here are a few references that I think you could gain more information from.
Case report of Brunner’s gland hyperplasia: A rare “mimic” of malignant pathology: https://www.sciencedirect.com/science/article/pii/S221026122100328X

The medical treatment is to control gastric hyperacidity, which is one cause of Brunner's gland hyperplasia. However, the regression of Brunner's gland hyperplasia is rare (7). Therefore, excision appears to be the treatment of choice." --- Brunner's Gland Hyperplasia: Treatment of Severe Diffuse Nodular Hyperplasia Mimicking a Malignancy on Pancreatic-Duodenal Area: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2526515/

While I find other people who can relate to your experience, can you tell me a little more about your situation?

I have had excessive belching and burping, for years but getting worse. People that I am with comment on this. I have nausea consistently and occ abdominal pain, and that is not a big concern for me.

@lakelady55, you may be interested in joining this discussion:
– How do you control uncontrollable Burping and Belching? https://connect.mayoclinic.org/discussion/uncontrollable-burping-and-belching/

I am working on my diet, and OC meds. At this time nothing is helping.

Hi LakeLady55,
Sorry you are dealing with this.

I have been diagnosed with Brunner’s gland hyperplasia (BGH) in my duodenum and foveolar hyperplasia in my stomach on my most recent endoscope. I have had a whole host of GI issues and various diagnosis over the years but I won’t get into that here because I think you are looking for information on how to get relief so I will not bore you with my details.

I have researched this quite a bit and also had found the articles the moderator provided here. Long story short, from what I understand (as a layman) is that the condition can be caused by bile reflux. I had my gallbladder removed so for me, it has caused bile to back up into the duodenum and stomach causing the change in the cells. I have tried a few medications like bile binders, prevalite, proton pump inhibitors, etc. Unfortunately, they have not provided much relief and some can make bloating worse.

Not sure if your BGH is caused by bile but it may be a question for you to ask you gastroenterologist about. If medications don’t work and you are symptomatic your doctor will need to thoroughly evaluate the situation. There are surgeries to divert bile further down in the small intestine that studies show improve BGH.

My doctor said it is benign so there is really not much to do. I question this tactic a bit because while it is usually a benign lesion, there are other case studies that show it can become malignant. Hence why it is so important to be sure what it is so no hugely invasive surgeries are done to remove it if it isn’t cancerous or causing a blockage.

I get reflux both bile and acid, vomiting bile (sometimes blood), abdominal distention, and abdominal pain. I have a whole host of other organ systems that are affected due to chronic inflammation so these symptoms just add to the list of things to overcome during the day. Since we are doing the wait and see approach, for symptomatic relief I try to rely on coping skills I learned with cognitive behavior therapy. Mind over matter is not what I am saying because what is happening in our bodies is not something that can be wished away. It is rather a set of tools that I use like relaxation techniques, distraction, pacing myself, etc. I have tried many diets like elimination, FODMAP, etc. but with little success. I have learned that things like tomato, onion, garlic, alcohol are triggers so I do best to avoid them. You may want to try keeping a good journal to see if you notice any patterns when you aren’t feeling well. Then try to remove those offending things.

Believe it or not my chiropractor suggested I start taking a charcoal supplement when my Brunners Gland Hyperplasia acts up. It works wonders, with laying down and putting heat on the area. Give me a couple hours and I’m good as gold until the next attack. I keep a good journal but also will have an attack if I have an empty stomach. No rhyme or reason sometimes. Thank you for the information.

I had an endoscopy a few weeks ago; I already knew I had Barrett's esophagus, but now they found I have fundic gland polyp and Brunner gland hyperplasia. My thing is, I have had pressure behind the left ribs, and I am anemic. My stomach swells up, and I have indigestion.