@ellerbracke I was on Anastrozole for clues to 3 yrs and I developed a trigger thumb. Mentioned to my oncologist regarding as a side effect. He said No, it wasn’t not from med. I researched and found a small plastic device called ‘Oval 8’. It worked for me. Probably in a week +:- a few days ( I can’t remember exactly) my thumb was back to normal. You can buy on Amazon. Here is Oval 8 website. https://www.3pointproducts.com/oval-8-finger-splint-copy-1 Very inexpensive. Good luck. Worth a try before doing surgery. Blessings