With your friend’s allogenic transplant she’ll need to be very vigilant with any new or unusual symptoms. She should not hesitate to inform her transplant team. Nothing is too small to report!
During the first 100 days of transplant, small infections or irritations can get out of control quickly because of her impaired immune system. The chemo used prior to transplant is very harsh. It cleans out the marrow so that the newly transplanted cells will be able to set up ‘housekeeping’ in a pristine environment.

Chemo destroys rapidly dividing cells, whether cancerous or normal cells in our digestive systems from mouth to intestines. So, very often there is painful irritation in the mouth and esophagus and sometimes of the stomach and intestines. This can cause nausea and diarrhea depending on how deeply irritation penetrates beyond the mucosal tissues.
Conditions can become acute and trigger graft vs host disease. That’s why symptoms need reported and treated quickly.

After about the 100 day mark, the body and new stem cells start playing together better and the new immune system will not be quite as aggressive. Reactions that used to develop quickly, will generally transpire at a slower rate.

The next 2-3 weeks should be the worst for your friend. Her blood numbers will start dropping as the chemo kills off her old blood cells. Her new stem cells should engraft in about 12 to 15 days(sometimes longer) and start producing new blood cells; Red, White and Platelets. At that point she’ll start feeling better slowly as the white blood cells run to the rescue! ☺️

She’s going to feel extremely low in energy and possibly spirits until that happens. There’s no way to rush engraftment so just be supportive and let her know she’s going to get through this!! There is life on the other side of transplant and it will be worth the effort…she’s getting a second chance at life. ☺️

I’m here for her (and you) any time. There are a number of us in the forum who have had allo transplants and will help bolster her up! Don’t hesitate to reach out.

Are you her caregiver during her transplant journey?

Good morning, @pgcdds I just wanted to check in with you to see if your friend is feeling any better. We chatted 4 days ago and at that time she was experiencing severe abdominal pain. There are many medications at the disposal of her transplant team to help her get through the worst of the side effects. I felt like my team of diligent nurses were my guardian angels!
With her transplant being only 10 days old, she’s coming into the thick of things right about now. But within a few days when her new stem cells engraft, she’ll begin to feel much better. Let her know this is just temporary. It’s worth the fight! ☺️
Do you get to visit with her in person?