1. < Prostate Cancer

Stage 4 prostate cancer treatment options

Posted by safari1949 @safari1949, Nov 17, 2019

I have recurring prostate cancer and it has found its way to 5 different bones, including my left shoulder and two ribs on my right side. I started 6 month Lupron shots but have been told that because it is stage 4 I need additional treatment. My oncologist is recommending either Abiraterone (Zytiga) for 33 months or 6 treatments of Docetaxel chemo. She says that they look to have very equal success. With the Zytiga I will also have to take steroids, probably prednisone which I understand includes possible liver damage. Six chemo treatments seems like a better approach but I have heard Zytiiga talked about in a very positive manner. I understand it can be expensive and I do worry my prescription drug coverage could change its formulary and raise my cost significantly as well. I've already had that happen with a drug I take for Parkinsons.. Just looking for some general input regarding peoples actual experience either way.

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melcanada | @melcanada | Nov 27, 2022
In reply to @melcanada "Was chemo oral like Enzalutamide? If not, why Enzalutamide chemo in a daily pill Xofigo Explain..." + (show)
@melcanada

Was chemo oral like Enzalutamide? If not, why Enzalutamide chemo in a daily pill

Xofigo Explain how it works on bone PC metastasis .

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https://www.medicalnewstoday.com/articles/drugs-xofigo#about found answers

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melcanada | @melcanada | Nov 27, 2022
In reply to @digger "Hi mine went to my ribs, sternum,scapula I had lupron with abitron 6 radiation treatments to..." + (show)
@digger

Hi mine went to my ribs, sternum,scapula I had lupron with abitron 6 radiation treatments to prostate psa down to .04 all was good in July they found a spot on my lumbar it is aggressive prostate cancer they said i would have to have chemo had 5 rounds of chemo,after third one tested said everything looked good but I would have to stay on chemo the rest of my life or till I can’t tolerate it,this was at Cleveland Clinic came to Florida after 5th chemo treatment Dr at Moffitt is taking me off chemo getting ready to start Xofigo which is radiation injections to blood once a month for 6 months it is supposed to be easy to tolerate I would ask about Xofigo before radiation see what they say chemo was tuff but do able best thing I recommend is exercise as much as you can no matter what you do I joined planet fitness good luck Dave

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https://www.medicalnewstoday.com/articles/drugs-xofigo#about

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digger | @digger | Nov 27, 2022

My chemo was through an IV takes about three hours once every three weeks, I don’t know anything about the other kind you were talking about, the Xovigo is radiation isotopes injected into your bloodstream like an IV it goes into the bones where the cancer is just like calcium is absorbed into your bones and it kills the cancer there’s a real good video on YouTube type in xovigo There’s a doctor that gives a good detail about the treatment you can learn a lot on YouTube look up anything you want see if that helps

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1 reply
melcanada | @melcanada | Jan 11 7:19am
In reply to @colleenyoung "Welcome, @herbg. What side effects are you experiencing and how do you manage them?" + (show)
@colleenyoung

Welcome, @herbg. What side effects are you experiencing and how do you manage them?

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After 1 year Enza has lost its effect on my bone mets in spine PSA 7.8 They offer Radium 223 at PMH

Any OS stats on this or effects I feel great at 79

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philnob | @philnob | Jan 12 7:21am

I was on Zytiga for a short time until I developed breathing problems, and had to discontinue using it. Since then, I had been on Orgovyx which get my PSA number below 1 for 2 years. Eventually, the metastasis builds up resistance to the Orgovyx, and my Oncologist has added Xtandi to my hormone therapy which is bringing the PSA number back down. The fatigue from Xtandi, so far,
is very difficult to manage, but I continue with exercise, and with my Oncologist’s approval I have decreased the dosage of Xtandi, and will know where I stand after my next blood work up.
I don’t know if this helps, and I wish you the best with your treatment.
Hang in there!
Philnob

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melcanada | @melcanada | Jan 12 8:12am
In reply to @digger "My chemo was through an IV takes about three hours once every three weeks, I don’t..." + (show)
@digger

My chemo was through an IV takes about three hours once every three weeks, I don’t know anything about the other kind you were talking about, the Xovigo is radiation isotopes injected into your bloodstream like an IV it goes into the bones where the cancer is just like calcium is absorbed into your bones and it kills the cancer there’s a real good video on YouTube type in xovigo There’s a doctor that gives a good detail about the treatment you can learn a lot on YouTube look up anything you want see if that helps

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As my Xtandi is failing after 1 year they plan Radium 223 or Xovigo a one minute injection every 4 weeks for six moths

Anyone has Overall survival stats of this treatment please 79 feel great

still on Xgeva and Zolodex

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leeaniel | @leeaniel | May 4 8:26am

I get my Abilaterone from India, South Delhi Pharma for $185 plus shipping. 120 x 250 mg generic tablets. I order via Whatsapp o. (India Meds)

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stephenjt1tx | @stephenjt1tx | Jul 23 4:54pm
In reply to @maxvt "About Lupron: I would like to hear from others 1) how long do the hot flashes..." + (show)
@maxvt

About Lupron: I would like to hear from others 1) how long do the hot flashes last after the “expiration HAHA date” of the previous injection, and 2) did any medications help alleviate these “flashes?”

My Urologist advised me to talk to my PCP about changing my antidepressant from Sertraline to Venlafaxine. I also read on one of these postings of someone taking Paxil.

Thank you for your time.

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I am 72 yrs old and had radical prostectomy in 2018, after surgery, I had psa start going up so I was signed up for radiation treatment, I had lupron shot before radiation and had only 3 months on lupron. I have had hot flashes and night sweats often since then. I have tried escitalopram, no help, and was suggested to try Black Cohosh, no help, I have requested Paxil from my psychiatrist, I will let you know when I try it if it helps.

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lm1 | @lm1 | Jul 24 9:53am

I was on lupron prednisone5mg and zytiga with 20 rounds of radiation when i was first diagnosed with psa13.4 after 18 months i stopped everything psa went to undetectable for 18 months then started climbing backup i had mets to the pelvis and the 9th rib and the spine and my ishium 3.4 tumer went for another 5 round of radiation and lupronpsa now is 0.05 pet showed tumer is shrinking mets are almost gone tried adding xtandi but my bloodpressure went thru the roof stopped it after 6weeks staying with the lupron getting my other hip replaced next month age 72 . feel pretty good.I guess ill stay with the lupron as long as it works until it gets resistant.then who knows.

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