I have been taking Actemra (tocilizumab) for almost 4 years. I have been mostly off prednisone for about 3 years. Actemra was prescribed for PMR but my rheumatologist needed to seek approval.

I was treated with prednisone for nearly 13 years and never could taper off. I tried several DMARDs which helped some but ultimately were stopped due to side effects. I now only take Actemra

I started with Actemra injections every two weeks which initially allowed me to taper off prednisone in 7 months. Actemra has controlled my PMR symptoms.

I haven't had any significant side effects from Actemra. My dose of Actemra has been adjusted several times. My pain returned gradually whenever Actemra was stopped.

I am currently doing a monthly infusion of Actemra.