I started on 15mg prednisone over two weeks ago after a confirmation by PET scan of pmr. I’m only 55 so going from being a 5 day a week runner, workouts, etc person it has been extremely difficult for me. 15 mg helped significantly but I had 2 areas that were stubbornly not decreasing in pain. My neck and shoulders and behind my knees. Specialist increased last week to 20mg which has helped the shoulders/neck but I still have pain behind my knees if I try to kneel - which I haven’t been able to do for months. Has anyone else experienced a stubborn spot that the prednisone doesn’t seem to help or at least to help significantly?