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Feedback on Linzess for Irritable Bowel-C or Chronic Constipation

Digestive Health | Last Active: Apr 14 6:19am | Replies (147)
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@denisef

nothing at all works for me - lifelong problem with constipation since childhood. only thing that works (like a dream) is Miralax. you can adjust the amount so that it works for you. i take double the recommended dose. one capful in the a.m. and one in the pm. sometimes if things are "slowing up" I take a heaped capful - and if too loose then I decrease it or skip one dose. you cannot take too much its an inert substance - just throw it into some hot tea or coffee and you won't even know it is in there. I have been taking it for about 8 years now - ONLY thing that works. I was taking a half box of laxatives at a time before. Terrible cramps. The miralax works every morning - like a charm - and mostly after that I am "done for the day" once in a while it gets a bit 'out of whack" in that I have to go again or get a bit backed up - but I just adjust the dose accordingly and I am back on track.

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woodspixie | @woodspixie | Nov 25, 2022

Have you been checked for MALS (and or other abdominal arterial compression syndromes)? Make sure a vascular surgeon is involved, and that the radiologist and whomever interprets it *knows about MALS*. Also, if they do Doppler US and or CTA, that they *use MALS protocols*; they must visualize this on *expiration* as well as inspiration. I ended up self-diagnosing this because it was missed by every physician I’ve ever seen. I ignored the recorded instructions on the CT and exhaled completely for one of the 3 images. My celiac artery was completely stenosed on expiration, and when they opened me up, they had to reperfuse 4 arteries, and my abdominal aorta was compressed, plus a bunch more was wrong they corrected but couldn’t see on imaging.

(MALS is also far more common in EDS-ers …just sayin’)

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