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DiscussionDid androgen deprivation therapy (ADT) cause bone loss for you?
Prostate Cancer | Last Active: Mar 23 7:43pm | Replies (18)Comment receiving replies
Replies to "Welcome @tott123. Osteoporosis can be a complication of androgen deprivation therapy (ADT) for prostate cancer. I'm..."
I haven't discussed the bone loss with any of my Docs. We are too focused on the cancer. I will at my next appointment bring it up and see if a new Dexa Scan is recommended. I am doing ADT for 20 more months . I am taking the appropriate vitamins, and exercising when the fatique allows. I accept that osteoporosis may be in my future and that it's part of the price of extended living w PCa.
Yes still taking ADT.
Did break spine before it was picked up. Thought just pulled my back. Went to a physiotherapist gave me exercises to do said I didn’t need an MRI. Wasn’t happy so I went for MRI privately. Picked up broken spine. Had a DEXA scan showed osteopenia.
Waiting to be referred to fracture clinic where they will give me more guidance probably on to medication for bone health.
I'm glad that you posed these questions. I just posed some of them to my oncologist just 5 hours before your post. It's not the first time.
So how's my prostate cancer treatment going? I think I am getting up-to-date treatment of the cancer, which began in April. I'm particularly appreciate the access to Hydrogel spacer placement prior to radiation. My large prostate was pressed up against my colon, so I'm crediting if for one reason I have no post-radiation colon changes. Lupron 2 months pre-radiation drove testosterone to zero, and my PSA down from 6.9 to 3.1, and six months later the PSA < 0.01. So, treatment is going well based on post-radiation symptoms and my biochemisty.
So, how's the treatment of the patient going? I'm managed by two docs who are doing great with the disease. No systematic outline or review of the likely effects of ADT treatment and how to manage each. Bone scans had revealed significant osteopenia and osteoporosis at a couple of major bones. ADT treatment is known to worsen this. I asked about what to do about it. They put me on Fosamax. Ok. No mention of calcium. My wife demanded I start taking calcium supplements. Each video visit I describe the debilitating effects of Lupron (weakness, stamina, weight gain, etc) and ask what I can do. I ask what is the data on effect of Lupron on disease or longevity; what are the tradeoffs given my age and health? Perhaps there are no simple answers. I'm thinking of dropping the remaining nine months of Lupron so I can regain sufficient health to return to enjoying life.
Bottom line: My high risk PCa treatment is in good hands. I'm struggling with managing the impact on my life.
What percentage of prostate cancer men develop osteopenia while on ADT? I've been on leuprolide for one year. I just had a Dexa scan and found out I have osteopenia, and apparently I will now always have it. Blue Cross wouldn't cover the costs so I had to pay for the test on my own. Why doesn't insurance cover Dexa scans for men? I believe they do cover women who have breast cancer and are on a similar hormone therapy.
Yes, bone loss is common with ADT. A year after my first Lupron shot I had a bone scan to check mine. I had 18 months of ADT in conjunction with Proton Therapy. The bone scan indicated bone loss and greater chance of fracture. Doctor at Mayo Phoenix had me take an infusion of Reclast to strengthen my bones until my testosterone level increased after the ADT treatment was over. Don't know if your doctor has discussed Reclast treatment, but is common for dealing with osteoporosis. My wife has started using it.