Good evening @joycemarie, I appreciate your response. I don't know if I understand your question about Duloxetine and Gabapentin. I take 120 mg of Duloxetine in the morning to control my anxiety which, if not controlled, leads to more pain. Then at bedtime, I take 600 mg of Gabapentin to calm down the numbness and tingling in my hands. So....two different medications at two different times for two different symptoms......don't know if they even interact. Maybe someone else will have a better answer for you.

May you be safe, protected, and free from inner and outer harm.
Chris

Hi @kathylewis, I took Cymbalta (deloxitine) with Gabbapentin for many years. The Cymbalta was given to me for depression. I was on max doses for many years. Cymbalta was one of the first I tried to reduce and wean off, as well as slowly lowering pain medications. This was not easy, as withdrawing pain for me was horrid. All the drugs seemed to be hurting me more than helping after 5 years. So getting on them easy, weaning off, slow and painful. I weaned off them one at a time to start with the help of medical cannabis. Long journey. The decision to get on or stay on/ increase these drugs should not be weighed lightly. Homeopathic cannabis topicals and tinctures have returned me to a quality of life that pharmaceutical drugs, and their side effects including withdrawal caused more pain, and maybe even damage. So combo with caution is my opinion in hind sight. I take .5 mg xanax twice a day now for anxiety and pain with my a small amount of Medical Cannabis. That's it! praise God! Regards, Don