I did 5 years of letrozole with pretty severe osteoporosis, and I was unable to take meds at the time (MD did not want to give them to me, long story). Bone density dropped the first year, much as it did after menopause, and then the drop was much less for the years after that.

There are several ways to manage this situation: Reclast, Prolia, Tymlos, Forteo, Evenity, during or after cancer meds.

I am on Tymlos now, after finishing cancer meds, and am much stronger. I have to say that tai chi and walking was very helpful while I was on AI's.

Bones can be managed more easily than more cancer!