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bronchiectasis and high eosinophil count

MAC & Bronchiectasis | Last Active: Aug 14 4:44am | Replies (19)
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@wangling

Hi @hcroom
Thank you. My pulmonologist said the other day that it is likely my high eosinophil count causes bronchiectasis. Your 60 years of dealing with high eosinophil count and 20 years of bronchiectasis, what a successful story. My pulmonologist said there is a new drug very effective for treating eosinophil count, it is called "IL4/IL5 inhibitor". Have you tried it?
Does your bronchiectasis condition get worse over the years or stay stable?
Best and be safe!
Ling

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Replies to "Hi @hcroom Thank you. My pulmonologist said the other day that it is likely my high..."
hcroom | @hcroom | Nov 12, 2022

I tried Fasenra which contains a monoclonal antibody directed against the alpha chain of the interleukin 5 (IL5) receptor. My eosinophil count dropped to zero!
After three years I decided the cost- benefit analysis didn't justify continuing this medication. I am sure there will be many meds directed against the action of these interleukins. The primary literature has shown already that some are more efficacious than others. All are expensive, even if insurance pays some of the cost.

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