I have been taking anastrozole for almost 3 months. I have few current side effects. The percentage of recurrence seems small even if I don't take it, but I have plans to discuss it further with my oncologist next month. I am most concerned about the long term cognitive and memory issues, because I won't know if or when they are occurring. I need to find out whether there are tests for side effects to the brain. I know he can monitor any potential bone loss, and there are therapies for this possibility. I do exercise. You're right; there are tough decisions.