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Capecitabine (Xeloda) side effects: how do you manage them?

Breast Cancer | Last Active: May 19, 2023 | Replies (30)
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@adanab

I have MBC to bone, and now to liver. Ibrance and Afinitor have both stopped working (immunotherapies) and I was started on oral chemo pill Xeloda. Full dose of 2000mg twice daily caused hand/foot syndrome (redness, pain, but no blistering) and mouth sores. It’s a 2week on, one week off regime. I took a break and am now on the same regime but at 1500mg twice daily. Would like to hear suggestions for mitigating side effects. Thanks.

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Replies to "I have MBC to bone, and now to liver. Ibrance and Afinitor have both stopped working..."
Colleen Young, Connect Director | @colleenyoung | Nov 11, 2022

Hi @adanab,
You might also get helpful tips from this related discussion:
- Mouth sores from chemo https://connect.mayoclinic.org/discussion/mouth-sores-from-chemo/

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seathink | @seathink | Nov 12, 2022

I had to go to a lower dose, one week on/one week off to lessen my hand foot syndrome. Calendula, spa socks and gloves, and all the ointments I'd used for radiation helped keep the cracking sort of to a minimum. Started to loose my toenails by the end, but I was only on it for a year. (Not MBC, just agressive S3 TNBC).

Hugs. 😟

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