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Experience with Methotrexate?

Polymyalgia Rheumatica (PMR) | Last Active: Jan 31, 2023 | Replies (91)

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@marieirene

In my last flare up I had swollen & painful hands. My markers were sky high. Got a shot & felt relief. She put me on methotrexate & I continue to take six 2.5 mg each Wednesday. Starting to taper prednisone to 10mg daily. I hope to get to the pain free stage without difficulty. I also take 1mg folic acid daily. I read where you shouldn’t take calcium tabs at same dosage time as prednisone so I don’t take them together.

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Replies to "In my last flare up I had swollen & painful hands. My markers were sky high...."

Hi, marieirene. Your post was really interesting and helpful. I could not remember the reason why I take these meds at different time of the day, so you reminded me. I also separate calcium and prednisone, but might move the calcium even later to a different time. So complicated.
My experience with tapering prednisone after starting Methotrexate was that the early stages were quite smooth, with no difficult flareups. As my dosage got smaller it would take longer to settle down, dropping by 1 mg every month. But it would settle down. Good luck.