I refused aromatase meds they first time I had breast cancer (4 yrs ago) w/lumpectomy & 3-day radiation for the same reason as you: quality of life. I have chronic pain from spine issues & ostopenia & just didn't want to risk even more pain in my life. I had a recurrance this year. This time I had lumpectomyw/3 weeks of radiation. I begrudgingly said yes & an on Letrozole since June. I had minimal side effects & after a HORRIBLE infusion reaction that lasted a week, I now have no side effects & my chronic pain has even lessened!! I never would have expected this result. So us UT worth a try? Perhaps.