Tymlos is a hormone treatment that is very effective in preventing spinal fractures by speeding up the building of bone. Caused cancer in lab rats (high doses). I've had success building bone by getting my Vit D up to snuff, following recommendations at saveourbones.com, eating prunes, taking Ca and some strontium. I quit Omparazole then Nexium after I learned about effects of PPIs on the kidney. I find that gargling with 8.8 pH alkaline water helps my throat, which is prone to irritation from GERD resulting from my hiatal hernia. The alkalinity neutralizes pepsin, the enzyme that digests protein and can also digest throat tissue. (I learned of this via a journal article from PubMed.) I also try to finish eating at least 4 hours before bedtime, use Gaviscon Advance aniseed suspension as a stomach block and antacid. My go-to antacid is Life Extension's Esophacool.