What is your diet? Have your docs chased down any food insensitiiiiiiiivities throu blood test? Have you tried to lower inflammation through diet? Have you had a recent endocrine workup? Thyroid, adrenal? What is vitamin-mineral status? (B12, D, E, ferritin? Your history leaves out what has worked for you and what you have tried personally that doesn't seem to work. Have you been checked for EBV antibodies? The resurgence of EBV followingCovid could account for continung declne and autoimmune activaton. I feel for your suffering and frustration, and prsy you find answers and healng soon.