I also am undecided whether anastrozole is worth the side effects. I had stopped for a week on the advice of my oncologist. I have pre-existing issues, including some family heart issues. My own heart issues are irregular heart beat and tachycardia, which have been deemed not to need treatment. My osteo-arthritis and dry eye syndrome [which I had before my lumpectomy] have been aggravated by the anastrozole. Yesterday I was instructed to go back on the anastrozole and call in a week if the dry eye and knee soreness get worse. There are so many negatives and not a lot of recurrence protection, at least what I was told. I have a 6% chance of recurrence without the hormone repressant and a 3% chance of recurrence if I take it for five years.
Has anyone heard of very different percentages of recurrence?