Hi @mglinkhart, Unfortunately, Ibrance didn't work for me. After 2 months of being on it, the scan showed my liver tumors had increased exponentially. So I went on Piqray. That was over the course of a year. I had digestion issues and eventually my hair started falling out. I found out later I had Neuroendocrine Breast Cancer (rare) so these treatments didn't work. Sometimes, when you start a drug, if the tumors are dying, they expand slightly. That can cause pain. I would give it a few more weeks to be sure if its working and do a blood test with cancer markers.
Good luck!