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Invasive Lobular Carcinoma Pleomorphic Level 3 (Oncotype Score 34)

Breast Cancer | Last Active: Jun 29 11:04am | Replies (36)
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@ilcpfightee

ER/PR and HER 2 Status- Invasive Lobular Carcinoma Pleomorphic Grade 3
This is just something I am pondering and thought maybe someone on the boards may know what it all means.

I am ER 70%, PR negative, and HER2 negative, with invasive lobular carcinoma, grade 3, pleomorphic.

If only 70% of my cancer is driven by Estrogen, and the other two things are negative, is something else also driving the growth?

Just curious, with two negatives and one that isn't 100% positive, I found it concerning.

Thanks for any insight anyone has!

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Replies to "ER/PR and HER 2 Status- Invasive Lobular Carcinoma Pleomorphic Grade 3 This is just something I..."
Colleen Young, Connect Director | @colleenyoung | Nov 2, 2022

@ilcpfightee, I'm following your thinking "If only 70% of my cancer is driven by Estrogen, and the other two things are negative, is something else also driving the growth?"

However, the determination of the presence or lack of hormone receptors is important to understand which treatments are effective, rather than considering what is "driving growth". The types of breast cancer that do not have hormone receptors are not affected by endocrine treatments aimed at blocking hormones in the body.

What treatments are you getting or have had? Are they treating your cancer like they would treat triple negative breast cancer?

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