Has she been tested for Lyme Disease? Sadly Lyme Disease doesn’t always show up in the standard blood test they use to check for it. The joint issue you mentioned made me think of Lyme. I had Lyme and every joint in my entire body hurt. It got to where I couldn’t hardly get up off the sofa. A rheumatologist tested me for Lyme and I only had one marker. I researched Lyme and I knew that is what I had. I contacted my general practitioner and she started me on the medication for Lyme. By day 5-6 my joint pain started to go away. Most people never know they have had a tick bite. I had a bite but never got the bullseye rash. Not everyone does. Our family had a place in Wisconsin near a lake, one of my nieces and her daughter both suffer from long term Lyme. If you feel she may have Lyme please find a Lyme literate doctor.