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Breast cancer-free anniversaries

Breast Cancer | Last Active: May 8, 2023 | Replies (117)

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@callalloo

For those who are unfamiliar with it, Evista is a SERM, rather than an aromatase inhibitor. [Tamoxifen is a SERM. I believe it was the first SERM for treatment of some breast cancer cases.]

An aromatase inhibitor blocks the production of estrogen while a SERM makes estrogen bio-unavailable for breast cancer cell receptors.

Because SERMS don't deplete the body of estrogen, patients on them do not have the bone density issues that patients on the aromatase inhibitors can face. Different drugs with differing mechanisms for 'starving' estrogen-sensitive cancers.

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Replies to "For those who are unfamiliar with it, Evista is a SERM, rather than an aromatase inhibitor...."

@callalloo I have spent 28 years dealing with glucose and insulin. My point was that demonizing "sugar" is more complicated. White rice is worse than ice cream, for instance, in terms of how fast acting the sugar is. And all carbs create glucose.

Fat is the other place post-menopausal estrogen can be found, apparently. I am too thin. I get calories where I can.

@lisajoann my docs would not allow more treatment. Glad you have flexible docs. I would consider a SERM for bones after Tymlos except I already have a clot risk.

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