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Breast cancer-free anniversaries

Breast Cancer | Last Active: May 8, 2023 | Replies (117)
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@lisajoann

Because it’s working for me! I want to keep all the estrogen I can out of my body…evista works to help bone density and at the same time keeps estrogen at bay!

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Replies to "Because it’s working for me! I want to keep all the estrogen I can out of..."
callalloo | @callalloo | Oct 21, 2022

For those who are unfamiliar with it, Evista is a SERM, rather than an aromatase inhibitor. [Tamoxifen is a SERM. I believe it was the first SERM for treatment of some breast cancer cases.]

An aromatase inhibitor blocks the production of estrogen while a SERM makes estrogen bio-unavailable for breast cancer cell receptors.

Because SERMS don't deplete the body of estrogen, patients on them do not have the bone density issues that patients on the aromatase inhibitors can face. Different drugs with differing mechanisms for 'starving' estrogen-sensitive cancers.

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