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Is anyone participating in a clinical trial for pancreatic cancer?

Pancreatic Cancer | Last Active: Jan 24, 2023 | Replies (28)
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@sprinter345

Hi
Which trial were you in ? Was your cancer metastasized? Which genetic component did they target ? Just got good news with scan - tumors are shrinking or unchanged even with having to have lower dosage of Gemabraxane and missing a treatment due to low platelets.
Your survival is very encouraging! Thank you for sharing.

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Replies to "Hi Which trial were you in ? Was your cancer metastasized? Which genetic component did they..."
stageivsurvivor | @stageivsurvivor | Oct 17, 2022

I was in the RucaPANC trial testing the PARP-1 inhibitor Rucaparib (Rubraca) for metastatic pancreatic cancer of either PDAC or PACC origin. Criteria included patients had to have failed one prior therapy and showed sensitivity to a platin-based regimen such as Folfirinox or Gemzar+cis-platin. I was responding very well on Folfirinox and had 24 cycles of it as well as 22 cycles of 5-FU+Leucovorin before entering the trial as study patient#1. Patients with somatic or germline BRCA1, BRCA2 or PALB2 mutations were eligible. I am (g)BRCA2 positive.

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