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Prostate lesions found, biopsy results, No symptoms

Prostate Cancer | Last Active: Jan 10, 2023 | Replies (54)
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@patof

Hi,
58 yo, PSA of 5.2 and DRE result was normal (negative). Assuming the DRE was well done, does a normal DRE result eliminate possibility of a T3 or T4 stage PCa?

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Replies to "Hi, 58 yo, PSA of 5.2 and DRE result was normal (negative). Assuming the DRE was..."
garye | @garye | Oct 16, 2022

My urologist confirmed my own extensive research - a DRE can be "hit or miss" as some PCa are located deep within the prostate, or on the bladder side, so not able to be felt with a DRE. My own DRE was 'normal' - but with my symptoms (LUT) and pains, I will have the mp-MRI with contrast this morning. Additionally, total PSA scores can be dramatically, "clinically significantly" reduced by NSAIDs, along with blood pressure and cholesterol medications. In another post, it was stated that if these meds are taken for more than 7 years, a total PSA score should be multiplied by a factor of 2.

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