Prostate lesions found, biopsy results, No symptoms

No it's still in there. I imagine it looks something like a prune (my imagination). The IMRT RADIATION is extremely focused. It delivers measured doses to the tumors and lymph nodes as needed. I have since had a PSMA PET/CT and it shows that the IMRT was a unequivocal success. My PSA went from 83 to 1.2 in 4 mos.. Its lower now (0.4) due to Zytiga. It's a journey
Spryguy

Hi everyone. I'm 58, got a PSA result 2 days ago of 5.2 and the urologist-oncologist informed be that a biopsy was required in coming weeks to confirm or not prostate cancer. He did not say much more, I was stunned by the news and had no questions. After much reading on several sites including Mayo Clinic, seems to me I should be waiting another 4-6 weeks and take another PSA test. Another point of interest is that I train a lot and had done 1.5 hours of cross fit the day before and the day of the blood sample to later read that I should have had 2-4 days without physical activity before the blood sample as it affects PSA test upwards by about 50-60%. Comments anyone… and thank you. Btw, I always have had lower urine flow for at least 25 years but never had any other urinal symptoms, always peed once or twice a night since my mid 20's...

Something else I should add, DRE was done and prostate was totally normal... blood sample was done same day for PSA...

I just turned 70; my PSA went from 3.5 to 7 in the past 9 months. Rechecked PSA 2 months ago to confirm rapid increase - 6.6. Urologist encouraged a biopsy, no hesitation from me - results indicated PCa, Gleason (4+3). Recent MRI indicates all cancer contained in the capsule. I have an appointment next week to discuss next steps but am thinking RP surgery.

Although the biopsy was uncomfortable, I’m very glad I went ahead with it. Treatment options are now very clear.

Given the info here, I'd probably schedule the biopsy for 2 ish mos out then take another Ultra Sensitive PSA test at the 6 week mark. Obviously, take the crossfit out of the picture for a few days prior, (although I've never heard that activity could raise the result by those numbers). If the result goes down significantly, you could always cancel the biopsy if that is no longer warranted.

Assuming your research is correct, you'd be within the normal range at a reduction of 45% would put you square in the normal category.

Also according to the NCRI ..."You should avoid sexual activity for 48 hours before a PSA test. This is because ejaculation can temporarily increase your PSA levels."

Although 5.2 is pretty high for a 58 year old, I think in those numbers trend is as / more important than the one reading itself. Had you had a test recently? Within the last couple years that you can compare this to?

Thank you @web265
Had no previous PSA tests done before. Blood sample for my PSA test was done about 30 min after DRE, again I'm reading this can increase PSA results by 50%.
All in all, I had had sex only 24 hours of blood sample, I had done intense exercise 5-6 hours prior to the blood sample and I had the DRE exam onle 30 min before the blood sample. Seems to me we are jumping a bit too fast on the invasive biopsy requirement. Yes for the MRI (actualy mpMRI), yes for second PSA and then decide on course of action... thx again, I'm new to all this and simply hope it was a ''bad' timing'' blood sample...

Hi,
58 yo, PSA of 5.2 and DRE result was normal (negative). Assuming the DRE was well done, does a normal DRE result eliminate possibility of a T3 or T4 stage PCa?

My urologist confirmed my own extensive research - a DRE can be "hit or miss" as some PCa are located deep within the prostate, or on the bladder side, so not able to be felt with a DRE. My own DRE was 'normal' - but with my symptoms (LUT) and pains, I will have the mp-MRI with contrast this morning. Additionally, total PSA scores can be dramatically, "clinically significantly" reduced by NSAIDs, along with blood pressure and cholesterol medications. In another post, it was stated that if these meds are taken for more than 7 years, a total PSA score should be multiplied by a factor of 2.

I was in the same situation as @garye , my DRE was normal, my PCa was all inside the organ.

I hope so as well! Fingers crossed for this to be the case! , but, I wouldn't let these thoughts guide you to anything but closely monitoring that PSA.

Best of Luck to you!