In February 2022 I started taking Verzenio, a 150 mg tablet twice a day. I was on that dosage for thirty days. I kept a daily diary of how I felt and the issues I had. Lots of intestinal problems. I alternated with diarrhea and constipation and had terrible stomach aches. A return of acid reflux which had been under control for years, my nasal allergies got really bad, plus nose bleeds. I was tired all the time and no ambition to do anything. Thank goodness for my team at Mayo, they were always available to answer any questions and offer solutions. After the 30 days it was decided I should reduce my dosage from 150 mg twice a day to 100 mg twice a day. After 12 days with no Verzenio I started on the new dosage. After the first 100 mg pill I developed a rash on my chest, neck and stomach by the afternoon it went away. That evening my heart started racing but stopped and seemed normal. The second day after lunch my stomach started really hurting. By three I was producing a large amount of mucus like I was having a major allergic reaction and started running a fever of almost 101 with chills and extremely fatigued. That third pill was my last, I was told to stop the Verzenio. It was a good decision, it took a few months for my heart to stop having the palpitations and my GI tract to get back to normal. I was disappointed I couldn't continue it, I think it was a good drug to try, I'm not sorry I did. Right now my health is fine, I just had a bone scan and mammogram which were both good. I continue to take Anastrozle with no side effects. I'm grateful for that, my supportive family, my Mayo team and the fact that I am alive with a good quality of life.