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Detection and treatment of microscopic cancer cells

Prostate Cancer | Last Active: Oct 31, 2022 | Replies (23)

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@robertkerr

Hi Colleen, my oncologist , like myself, is very focused on the rapid increase in PSA It's gone from 0.032 on 5/11/21, to 0.30 on 20/5/22, 0.39 on 4/7/22 and 0.70 on 10/9/22. I have had 3 scans, 2 PSMA PET CT scans and 1 FDG PET CT Scan. The latter on 13/09/22 stated no definite FDG-avid metastasis identified. The previous PSMA PET scans also did not show any avid disease. My oncologist believes that I have micrometastatic prostrate cancer. I should also mention that back in February 2021 I had an esophagectomy due to cancer of the oesophagus, This was followed by 24 weeks of chemotherapy. The scans showed was no sign of malignancy relating to that cancer.
We decided that I should have another PET PSMA scan after prior checking of my PSA. This will take place last week of November and I will be seeing my oncologist on 2nd December. Treatment will depend on the results but he is leaning towards ADT possibly combined with XRT. In the meantime he is looking to see where I can get a CTC test in Brisbane, Queensland.

It would be very useful if it's possible to locate further results ( since Oct 2018) of the SPPORT trial by Dr Pollack, University of Miami.

Thanks again for all your help and support, and please thank the prostrate cancer participants for their help and support.

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Replies to "Hi Colleen, my oncologist , like myself, is very focused on the rapid increase in PSA..."

Robert, that sounds like a very logical plan of action and surveillance. You sound like it sits well with you.

You asked about the results of the SPPORT trial. I found this published in May 2022:
- The addition of androgen deprivation therapy and pelvic lymph node treatment to prostate bed salvage radiotherapy (NRG Oncology/RTOG 0534 SPPORT): an international, multicentre, randomised phase 3 trial https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)01790-6/fulltext

Did you take part in the trial?