Sorry I didn't get to this sooner, but, assuming they are doing a trans rectal biopsy which I think is the most common. It can be done in office or hospital setting, my doc gave me a choice. I elected to do it in the office.

I was prescribed some heavy antibiotics to take a few days before and after. In the office they gave me another antibiotic injection. There's no polite way to say this so I won't try, they basically take a device and sort of shoe horn your anus open and work through there. They gave me a local anesthetic it wasn't all that painful, I'd call it uncomfortable, but very weird. They use a long syringe type device to take cores out of the prostate for testing, in my case 12, I've heard other numbers.

After the biopsy I didn't have much pain but the first bowel movement had some pain I wasn't expecting, that was a bit shocking. You may have some blood in your urine (I didn't) and you may see blood in your ejaculate, that I did have in varying degrees till the robotic surgery.

Best of Luck to you!

I get the "scary " part. I'm 1 year into PCa and "scary" is now background noise.
The biopsy isnt fun but is tolerable with blood in urine and semen for a couple weeks.
I started at local providers and my level of disease was under diagnosed.
Contacting Mayo was my best move (6 most into treatment). My level of PCa went from intermediate risk to aggressive, high risk. That was scary. My wife was at the consult and nearly fell off her chair.
It takes time to accept the reality of cancer. I'm happy to field any questions
Good luck on the biopsy.