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Non dectable PSA post Robot RP

Prostate Cancer | Last Active: Oct 10, 2022 | Replies (19)

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@kepasa

Undetectable is not zero, but below a minimum to clarify, ,

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Replies to "Undetectable is not zero, but below a minimum to clarify, ,"

What is that number? I've never heard anything definitive. There seems to be a lot of different opinions on it.

Also, has anyone heard of a clinical definition of Biochemical recurrence in terms of actual PSA numbers? This is more of a regulatory question regarding my employment (DOT physical) as opposed to a treatment question. The NIH just says a "rise in PSA", this must have been written before USPSA was common.

Steven J. DiBiase, Stephen C. Jacobs, in Prostate Cancer, 2003 say "
Clinicians should define biochemical recurrence as a detectable or rising PSA value after surgery that is 0.2 ng/mL or greater with a second confirmatory level of 0.2 ng/mL or greater."

Not really sure if that's a settled thing though.