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@barbakp

Great comment. The older drugs do have a track record and you can at least get good information. Fosamx is usually given easily (now a generic) ..but if you take the “holiday” know that it stays in your system for 10 years!!! Some holiday!! There are others in the same category that, if you stop them, they leave out of your system within a couple of weeks. Worth looking.

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Replies to "Great comment. The older drugs do have a track record and you can at least get..."

What I've read is that fractures often occur when one of the drugs that builds bone density fast is stopped because the bone loses its density fast.

The holiday means not taking the drug. I guess continuing to take it would result in a kind of overdose as it stays in the body.

My doc is not prescribing Prolia, the drug you are referring to that leaves quickly, because that sudden drop off brings sudden increased risk of fractures. He says breaks are possible with biphosphonates, because they linger, but you cannot take a break with Prolia unless you go on something else.