I did two full years of Lupron injections. They ran out of it and gave me Eligard instead. Yes. It was more painful. I believe I got it in the stomach instead of rear-end. I never had immunotherapy. I may get it if it starts spreading. It is in my lymph nodes. I am 76. Cancer was diagnosed when I was 72. The doctors gave me five years. The best way to fight it is thru exercise and diet. So far, it is working. I see my medical oncologist this Thursday and get all my blood tests including PSA and testosterone. My wife and I are working hard on getting an erection. So far, nothing. I do get a feeling that if I am ejaculating, it is going inside.