In the middle of editing, it stopped letting me edit so here is the final post. A little different than above.

Hi. So I take LDN and have for a few years. The thing with it is it actually works holistically. In a very low dose, it shuts down your adrenals for about 3 hours while you sleep. The lower the dose the better. After that your endorphins kick into high gear and becomes a kind of "runners high" in that your endorphins go into overdrive. Helping reduce pain. It's so cheap and old, no drug companies want to do research! No money in it.

There is lots written about it online and millions are starting to take it. It's been known to cure Parkinsons, MS and even some cancers. There is a huge long list of medical problems it's been thought to help. It resets your adrenal glands. There is a pharmacist in FL who has his whole family on it. I spoke with him for an hour as I researched it for nearly a year before stating it. Very knowledgeable but there are secrets to it. And it's becoming so popular many pharmacies are mixing their own and might not be using short acting, and pressed the right way and potentially bad powders from bad overseas manufacturers. There is no brand name anymore, it's all generic so you can't just assume it's all equal as it's all the rage and unlike Stan (pharmacist) in FL, some don't know how to do it right.

You can't take any pain medicine when on it as this low dose med blocks the effects. I came off for surgery and didn't get right back on but now I've been on it for almost two years again. You don't always know it's actually helping until you come off sometimes so people stop after a month. It's a long game treatment. It can take even 2 years to start helping so any short study won't work and even comparing it to a control group is useless as all people have adrenal issues so it's not about an "illness" to cure in a month. I can't imagine any study that would show it works as you really need to plan on a ten year study with illnesses and without. The how many on it (%) didn't get cancer that the % of the gen pop did. That kind of thing.

Definitely worth looking into if you treasure wholism. Our adrenals are a mess. All of us. Children too. Stress. Adrenal insufficiency esp which is rarely diagnosed by western med but is real like I'm sure you know.

More and more illnesses are being found to be autoimmune. This is a real treatment worth trying for autoimmune conditions. It's just been FDA approved for CRPS I think (only off label use approval for LDN - some hope for a disease for which there is no treatment. Helps fibro etc.

I don't know about this study but please research it and don't eliminate it thinking it's just another drug. It's an anti-drug when used in tiny doses. It kind of functions like a homeopathic in my mind. Give a little to spark a big response. Check it out, seriously. NOT the 50mg! And naltrexone 50mg is not used to reverse an overdose. It does not remove an opioid from your body. Totally different drug. This is taken daily like the old Antabuse where the person has to want to stop using. Kind of the anti-methadone.

People who take the full 50 can actually die trying to get high. You can't get high on it so the chances of an overdose is higher as they can "die trying." You have to be willing to quick all opioids to use it.

Please research it.

I am not giving endorsement for the use of a med. This still needs to be ordered by your doctor and not many doctors understand even what it is. My doc has down I take 50/day so my insurance company probably thinks I'm a drug addict. As a nurse I mix it myself so 30 pills, about $20 lasts me about a year and a half! Best of luck all. I'm all about LDN as you can tell. It's hope for the hopeless.

But it's a long game. If you are not willing to give it more than a year, then I would say don't bother.