Since I have Crohn's (45yrs) and PMR I have had plenty of pred. And when you need it only it will help. I have found ways to cope with some of the side effects. At higher doses, the restless legs are a real bummer. I use elastic bands to excercise my legs until they are really tired. Then I can rest. As for the moon face, well, I'm glad for the masks we have been wearing. My optothamologist has been doing handsprings trying to keep sight in my right eye. Fat deposits, yup, I've got a few. I have to convince new docs that it isn't my thyroid. (Labs say not.) I'm convinced that the recent brush with breast cancer is because the pred told my body to ignore abnormal cells. (Found it early thanks to routein screenings so don't put yours off.) So does prednisone complicate your life? You bet but it is better than the alternative.