Had the procedure 6 years ago and relapsed 9 months later. Speaking of cell collection, I had a Hickman catheter surgically implanted in my chest because the veins in my arms couldn’t be used. Believe it or not the device failed the day of cell extraction. Fortunately I had great nurses who were able to extract enough cells through my dried up arm veins. I had no cytokine release problems after the procedure but I believe a terrible reaction to the chemo before the re-engineered cells were reinserted. In hospital for 20 days instead of 10 because my peripheral neuropathy was so bad. After the relapse I found Keytruda a checkpoint inhibitor as my last resort. Merck gave me the drug for free as it was not approved by the FDA as a mercy case. Five years later I am obviously here. Oncologist feels the Re-engineered cells in combo with the checkpoint inhibitor Keytruda gave me more time. Keytruda overstimulated my immune system and is attacking healthy cells causing all kinds of problems in my body. Cytokine release is very common. In this case believe it or not is good. If you don’t have problems like Bob mentioned, the treatment didn’t work and that was me. I think my oncologist knew I would eventually relapse but didn’t mention it as she couldn’t be sure. Anyone with opportunity to get CAR should go for it. There are patients 10 years in. Immunotherapy right now is the gold standard for people like us who were failed by RCHOP.