@cheriels. My situation was different from yours. I didn't have radiation or any other treatment right after the hysterectomy. I had a recurrence of the same Endometroid Adenocarcinoma two years later. I had been going to Mayo Clinic every 6 months for follow-up and my nurse practitioner in the GYNOncology department found a little polyp on my vaginal cuff that turned out to be the recurrence. I had 25 external pelvic radiation treatments and 2 internal (brachytherapy) treatments. Before I started the radiation the radiation oncology nurse and the radiation oncologist both spent a long time with me to explain any side effects I might have. I had only a few of the side effects and these were mild. I had some bladder irritation that felt a little like a bladder infection - not terrible but I could feel it. That happened about half way into the treatments. I had diarrhea occasionally and I took the recommended Imodium when that happened. I had some fatigue but only for a day or two. I had some fatigue for about 2-3 weeks after the radiation therapy was finished and that gradually went away.

The radiation oncologist told me that I should do some exercise every day He said that this would prevent me from feeling too fatigued and if I laid on the sofa all day I'd feel even more fatigued. Those were his exact words. He was so right about that. I walked every day by parking at the garage that was the farthest away from radiation oncology at Mayo so that meant I walked the length of the tunnel from one end to the other every time I had radiation therapy which was 5 days a week. I kept up with my strength training twice a week by meeting with a trainer virtually on my computer. I did yoga. I rested and took a little nap when I was tired but I didn't linger with those naps.

The question of how the cancer can spread is something to ask your radiation oncologist. They will have a very complete answer for you. Since your endometrial cancer is FIGO Grade 3 that means it's a more aggressive type and so it's possible that the radiation therapy is meant to be preventive.

I hope this helps. Will you let me know when your appointment is scheduled and what you find out?