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@stageivsurvivor

Early in my treatment on Folfirinox for metastatic disease to the liver, I got genetically tested and found to have a gene mutation. When the effectiveness of Folfirinox began waning, I enrolled in a clinical trial in 2014. I had a complete response resulting in NED since.

There are many types of clinical trials that are not dependent on having a gene mutation. There are drugs designed to interrupt/shut down the cell energy cycle of malignant cells. Immunotherapy targeting check-point inhibitors is another area of active research. PanCan.org and LetsWinPC.org have a clinical trials finder as does clinicaltrials.gov. There are several companies that will help narrow down potential trials that do the searches at no charge. Look into the websites EmergingMed.com, CancerCommons.org, myTomorrows.com and Ancora.ai. Clinical trials offer late-stage pancreatic cancer patients the potential for better outcomes.

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Replies to "Early in my treatment on Folfirinox for metastatic disease to the liver, I got genetically tested..."

Thank you! We will start checking into these.

What specific clinical trial were you in? And is it standard of care now?

Hi
Which trial were you in ? Was your cancer metastasized? Which genetic component did they target ? Just got good news with scan - tumors are shrinking or unchanged even with having to have lower dosage of Gemabraxane and missing a treatment due to low platelets.
Your survival is very encouraging! Thank you for sharing.